HFC/HC BlendA1 Safety ClassGWP 2,270
Refrigerant Technical Guide

R438A RefrigerantMO99 / KDD5 · A1 R22 retrofit blend · broad legacy equipment relevance

R438A, widely known as ISCEON MO99 or KDD5, is a nonflammable retrofit refrigerant developed mainly for existing R22 equipment. It was designed to provide a relatively easy R22 transition path while keeping A1 safety, which is why it became one of the most recognized retrofit blends in legacy HVAC and refrigeration service work. Today, its practical relevance remains high in the installed base, even though its GWP is far above modern low-GWP targets.

Technical review updated: August 27, 2026
R438A at a glanceReference data
Composition / FormulaR32 / R125 / R134a / R600 / R601a = 8.5 / 45 / 44.2 / 1.7 / 0.6HFC/HC Blend
100-Year GWP2,270Current page reference
Safety ClassA1ASHRAE classification
ODP0Ozone depletion potential
Phase BehaviorZeotropic blendHow the refrigerant behaves
Why it mattersEPA composition and SNAP tables identify R438A (KDD5 / ISCEON MO99) as an A1 retrofit-oriented R22 alternative.Technical context
Overview

What is R438A refrigerant?

R438A is important because it is a real field refrigerant, not just a catalog number. EPA composition tables identify the blend as 8.5% R32, 45% R125, 44.2% R134a, 1.7% R600 and 0.6% R601a. EPA SNAP tables commonly show ODP 0, GWP 2,270 and A1 classification, with acceptability in multiple legacy air-conditioning and refrigeration end uses. That makes R438A a strong knowledge topic wherever readers still manage large populations of R22 equipment.

R438A, widely known as ISCEON MO99 or KDD5, is a nonflammable retrofit refrigerant developed mainly for existing R22 equipment. It was designed to provide a relatively easy R22 transition path while keeping A1 safety, which is why it became one of the most recognized retrofit blends in legacy HVAC and refrigeration service work. Today, its practical relevance remains high in the installed base, even though its GWP is far above modern low-GWP targets.

Technical Snapshot

R438A technical properties

Core reference data and selection notes for R438A based on the positioning used in this page.

DesignationR438AASHRAE designation; MO99 / KDD5
Nominal compositionR32 / R125 / R134a / R600 / R601a = 8.5 / 45 / 44.2 / 1.7 / 0.6EPA composition table
Refrigerant typeZeotropic blendMulti-component retrofit blend
ODP0No ozone depletion
100-year GWP2,270EPA SNAP tables
Safety classificationA1Nonflammable
Primary roleR22 retrofit refrigerantAir conditioning and refrigeration
Trade namesISCEON MO99, KDD5Widely recognized names
Service positioningLegacy system retrofitInstalled-base management
Selection themeEase of R22 transition with A1 safetyField-service relevance
Applications

Where R438A is used

These are the most relevant application contexts for R438A in practical HVACR and thermal-system discussions.

Residential and light-commercial AC / heat pumps

EPA SNAP tables list R438A as acceptable in these legacy categories.

Industrial process air conditioning

EPA also lists R438A in industrial process air conditioning.

Commercial refrigeration

R438A appears in multiple legacy refrigeration service discussions.

Household and stand-alone equipment legacy contexts

It has been listed in several historical SNAP end-use tables, though not all new high-GWP uses remain favored.

Installed R22 base management

Useful where owners need continued support or staged transition of older systems.

Service retrofits

Often considered when full equipment replacement is not yet practical.

Deep Dive

Detailed analysis

Why R438A became one of the best-known R22 retrofit blends

R438A earned real market attention because it targeted a massive installed base of R22 equipment. Owners wanted something easier than full replacement, and contractors often preferred an A1 refrigerant that fit familiar service practice more comfortably than flammable alternatives.

This gave R438A lasting relevance in retrofit conversations and field-service education.

As a result, an R438A page should speak to real installed-base decision making, not just list composition percentages.

R438A is practical, but it is not a low-GWP future solution

With a GWP of 2,270, R438A is much cleaner from an ozone perspective than R22 because it has zero ODP. But from a climate perspective, it is still a relatively high-GWP refrigerant.

That means its value is mostly practical and transitional: helping support or extend legacy systems, not defining the final destination of refrigerant transition strategy.

Content that explains this dual reality is much more credible than simple sales language.

Why the tiny hydrocarbon fractions matter

R438A includes small amounts of R600 and R601a in addition to the main HFC components. These small fractions help tune overall system behavior and retrofit performance.

However, the finished blend remains classified A1. That is why the page should always focus on the finished refrigerant classification rather than overinterpreting individual component flammability.

This also shows why a blend-specific detector and proper refrigerant identification matter.

When R438A content is still valuable for SEO and GEO

Even though the industry is moving toward lower-GWP options, search demand around R22 retrofits remains relevant because installed equipment persists for many years.

Readers often search R438A when they are making a real service or asset-management decision, which makes it a strong intent-driven topic.

That is exactly the kind of evergreen-but-practical content cluster a refrigerant site should keep building.

Comparison

R438A vs R427A

A focused side-by-side comparison to help readers understand selection differences.

Comparison PointR438AR427A
Primary roleR22 retrofitR22 retrofit
Safety classA1A1
ODP00
100-year GWP2,2702,140
TypeZeotropic HFC/HC blendZeotropic HFC blend
Special noteContains small hydrocarbon fractionsNo hydrocarbon fraction
Field positioningVery common retrofit referenceEasy retrofit positioning
Safety

R438A safety: A1 helps, but blend handling and retrofit validation are still essential

R438A is A1, which is one reason it became popular in retrofit work. However, it is still a pressure refrigerant blend, and retrofit suitability should be verified in the actual system. Correct charging, oil assessment, control behavior and performance checks remain part of good practice.

  • A1 classification: No lower-flammability label.
  • Blend service practice: Use correct PT chart and charge as a blend.
  • Retrofit review: Check the real equipment rather than assuming universal compatibility.

Leak detection

Leak detection should be validated for halogenated refrigerants and, where relevant, the finished R438A blend behavior. Portable service detectors and fixed monitoring systems solve different problems and should not be treated as interchangeable. GasNose provides a helpful broader reference point for refrigerant detection planning.

Explore refrigerant detection resources

U.S. regulations

EPA SNAP tables list R438A with ODP 0, GWP 2,270 and A1 safety, and they show acceptability in multiple legacy air-conditioning and refrigeration categories. At the same time, newer U.S. transition policy trends make very high-GWP HFC blends less attractive for new long-term strategies.

EU / international context

In Europe, R438A is similarly best understood as an installed-base or retrofit refrigerant, not as a leading low-GWP choice for new projects.

Phaseout / long-term view

R438A is not an ozone-depleting refrigerant, but its relatively high GWP limits its long-term strategic appeal. It remains most relevant where legacy R22 equipment still needs support.

Common Questions

Misconceptions to avoid

Several refrigerants are misunderstood because readers focus on one number or one trade name. These points help keep the topic accurate.

“R438A is a low-GWP refrigerant because it replaces R22.”

It has zero ODP and practical retrofit value, but a GWP of 2,270 is still high.

“R438A is just R22 with a new label.”

It is a distinct five-component blend with different properties and service behavior.

“A1 means any R22 system can use it without checks.”

Retrofit suitability still depends on the actual equipment and service condition.

“The hydrocarbon components make the finished blend flammable.”

The finished refrigerant is still classified A1.

Related refrigerants and alternatives

  • R427AAnother widely used A1 retrofit path for R22 systems.
  • R407FA1 transition blend more associated with commercial refrigeration than R22 comfort-cooling retrofit.
  • R513ALower-GWP A1 option, though for a different application family.
Frequently Asked Questions

R438A refrigerant FAQ

Concise answers to common questions about properties, uses, safety class and regulatory context.

What is R438A?

R438A is an A1 retrofit refrigerant, also known as ISCEON MO99 or KDD5, used mainly for R22 systems.

What is the composition of R438A?

EPA composition tables show 8.5% R32, 45% R125, 44.2% R134a, 1.7% R600 and 0.6% R601a.

What is the GWP of R438A?

EPA SNAP tables commonly show 2,270.

Is R438A flammable?

No. It is classified A1.

What is R438A used for?

Primarily R22 retrofit work in legacy air-conditioning and refrigeration systems.

Is R438A a pure refrigerant?

No. It is a blend.

Why is R438A still important?

Because many legacy R22 systems are still in service and need practical retrofit guidance.

Is R438A future-proof?

No. It is mainly a practical transition refrigerant, not a modern low-GWP endpoint.

What is the trade name of R438A?

The best-known names are ISCEON MO99 and KDD5.

How should R438A leaks be detected?

Use leak detection suited to halogenated refrigerants and the intended maintenance or monitoring task.

References

Authoritative sources

Primary EPA references are prioritized, with supporting official or technical industry sources where helpful.

Need help selecting or monitoring refrigerants?

Refrigerant choice is not only about GWP. Safety class, end use, machinery design, regulations and leak detection strategy all matter. If you are evaluating a transition project, ask for technical support.

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