Refrigerant Knowledge Center

What Is R454B Refrigerant? Properties, Uses and Safety

R454B is an A2L HFO/HFC blend selected for new air-conditioning and heat-pump platforms as a lower-GWP alternative to R410A, with different flammability and equipment-design requirements.

DesignationR454B
FamilyHFO/HFC blend
Safety ClassA2L
GWP467
ODP0
Lifecyclecurrent

What Is R454B?

R454B is an A2L HFO/HFC blend selected for new air-conditioning and heat-pump platforms as a lower-GWP alternative to R410A, with different flammability and equipment-design requirements.

R454B is classified as zeotropic blend in the HFO/HFC blend family. Its composition is 68.9% R32 / 31.1% R1234yf by mass. Refrigerant choice is never based on designation alone: capacity, pressure, lubricant, controls, heat-exchanger behavior, safety standards and local rules all matter.

R454B Technical Properties

General reference values for comparison; a current product specification and applicable regulatory basis govern a transaction.

Refrigerant designation R454B
Chemical family HFO/HFC blend
Composition 68.9% R32 / 31.1% R1234yf by mass
Blend type zeotropic blend
ASHRAE safety class A2L
100-year GWP 467 (IPCC AR5 100-year, manufacturer-reported)
Ozone depletion potential 0
Normal boiling reference -50.5 °C
GWP basis matters: different IPCC assessment reports can assign different values to the same refrigerant. Use the value specified by the regulation or procurement standard that applies to your project.

Common R454B Applications

Typical references include new residential and light commercial air conditioning, and heat pumps.

New Residential And Light Commercial Air Conditioning

Use depends on equipment design, operating envelope and applicable local requirements.

Heat Pumps

Use depends on equipment design, operating envelope and applicable local requirements.

Advantages and Limitations

Selection advantages

  • Established refrigerant designation with published reference data.
  • Application history in new residential and light commercial air conditioning.
  • ODP reference of 0.

Important limitations

  • A2L safety controls must be applied.
  • GWP and lifecycle status can affect long-term selection.
  • No refrigerant should be treated as a universal drop-in.

Environmental Impact and Regulation

Listings and transition dates are end-use and jurisdiction specific; confirm the current rule and equipment certification before purchase.

R454B has an ODP reference of 0 and a stated GWP of 467 using IPCC AR5 100-year, manufacturer-reported. Regulations commonly distinguish between manufacturing or import, new equipment, servicing, recovered material and individual end uses.

Verification date: July 2026. Confirm current rules with the competent authority for the destination and equipment category before making a compliance decision.

Safety, Handling and Storage

R454B is intended for approved equipment and is not a universal drop-in; follow manufacturer instructions and all A2L installation and servicing controls.

The A2L classification describes toxicity and flammability groupings; it does not by itself approve a refrigerant for a particular system. Review the current safety data sheet, cylinder label, transport classification, equipment manual and local code.

R454B Alternatives and Comparisons

Candidate alternatives must be evaluated as system choices, not simple chemical substitutions.

R410A

HFC blend; A1 safety class; GWP 2088 on the stated IPCC AR4 100-year basis.

Read the R410A guide

R32

HFC; A2L safety class; GWP 675 on the stated IPCC AR4 100-year basis.

Read the R32 guide

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R454B Frequently Asked Questions

What is R454B made of?

68.9% R32 / 31.1% R1234yf by mass; it is categorized as zeotropic blend.

What is the safety class of R454B?

The published classification used in this guide is A2L. Equipment approval and local safety rules still apply.

What is the GWP of R454B?

The reference here is 467 on the IPCC AR5 100-year, manufacturer-reported basis. Other assessment bases may show a different number.

Can R454B replace another refrigerant directly?

No universal drop-in claim is made. Compatibility and conversion requirements must be confirmed for the exact equipment.

Where is R454B commonly used?

Typical applications include new residential and light commercial air conditioning, and heat pumps, subject to equipment design and local approval.

References and Technical Sources

Source data is summarized for general education. Always use current official documents, standards and supplier-specific safety and technical data for engineering or compliance decisions.

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