Refrigerant Knowledge Center

What Is R507A Refrigerant? Properties, Uses and Safety

R507A is an A1 azeotropic HFC blend used in low- and medium-temperature refrigeration, offering stable blend behavior but a very high GWP that materially affects its long-term suitability.

DesignationR507A
FamilyHFC blend
Safety ClassA1
GWP3985
ODP0
Lifecyclephase-down

What Is R507A?

R507A is an A1 azeotropic HFC blend used in low- and medium-temperature refrigeration, offering stable blend behavior but a very high GWP that materially affects its long-term suitability.

R507A is classified as azeotropic blend in the HFC blend family. Its composition is 50% R125 / 50% R143a by mass. Refrigerant choice is never based on designation alone: capacity, pressure, lubricant, controls, heat-exchanger behavior, safety standards and local rules all matter.

R507A Technical Properties

General reference values for comparison; a current product specification and applicable regulatory basis govern a transaction.

Refrigerant designation R507A
Chemical family HFC blend
Composition 50% R125 / 50% R143a by mass
Blend type azeotropic blend
ASHRAE safety class A1
100-year GWP 3985 (IPCC AR4 100-year)
Ozone depletion potential 0
Normal boiling reference -46.7 °C
GWP basis matters: different IPCC assessment reports can assign different values to the same refrigerant. Use the value specified by the regulation or procurement standard that applies to your project.

Common R507A Applications

Typical references include low- and medium-temperature commercial refrigeration, and industrial refrigeration.

Low- And Medium-temperature Commercial Refrigeration

Use depends on equipment design, operating envelope and applicable local requirements.

Industrial Refrigeration

Use depends on equipment design, operating envelope and applicable local requirements.

Advantages and Limitations

Selection advantages

  • Established refrigerant designation with published reference data.
  • Application history in low- and medium-temperature commercial refrigeration.
  • ODP reference of 0.

Important limitations

  • A1 safety controls must be applied.
  • GWP and lifecycle status can affect long-term selection.
  • No refrigerant should be treated as a universal drop-in.

Environmental Impact and Regulation

High-GWP restrictions and quota pressure affect availability and permitted uses differently across jurisdictions and equipment sectors.

R507A has an ODP reference of 0 and a stated GWP of 3985 using IPCC AR4 100-year. Regulations commonly distinguish between manufacturing or import, new equipment, servicing, recovered material and individual end uses.

Verification date: July 2026. Confirm current rules with the competent authority for the destination and equipment category before making a compliance decision.

Safety, Handling and Storage

Confirm pressure ratings, lubricant requirements and the approved retrofit route before changing an existing R507A or R404A system.

The A1 classification describes toxicity and flammability groupings; it does not by itself approve a refrigerant for a particular system. Review the current safety data sheet, cylinder label, transport classification, equipment manual and local code.

R507A Alternatives and Comparisons

Candidate alternatives must be evaluated as system choices, not simple chemical substitutions.

R448A

HFO/HFC blend; A1 safety class; GWP 1273 on the stated IPCC AR5 100-year, manufacturer-reported basis.

Read the R448A guide

R449A

HFO/HFC blend; A1 safety class; GWP 1282 on the stated IPCC AR5 100-year, manufacturer-reported basis.

Read the R449A guide

R452A

HFO/HFC blend; A1 safety class; GWP 1945 on the stated IPCC AR5 100-year, manufacturer-reported basis.

Read the R452A guide

R454C

HFO/HFC blend; A2L safety class; GWP 146 on the stated IPCC AR5 100-year, manufacturer-reported basis.

Read the R454C guide

Need a commercial quotation?

Review packaging, documentation and inquiry requirements for R507A.

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R507A Frequently Asked Questions

What is R507A made of?

50% R125 / 50% R143a by mass; it is categorized as azeotropic blend.

What is the safety class of R507A?

The published classification used in this guide is A1. Equipment approval and local safety rules still apply.

What is the GWP of R507A?

The reference here is 3985 on the IPCC AR4 100-year basis. Other assessment bases may show a different number.

Can R507A replace another refrigerant directly?

No universal drop-in claim is made. Compatibility and conversion requirements must be confirmed for the exact equipment.

Where is R507A commonly used?

Typical applications include low- and medium-temperature commercial refrigeration, and industrial refrigeration, subject to equipment design and local approval.

References and Technical Sources

Source data is summarized for general education. Always use current official documents, standards and supplier-specific safety and technical data for engineering or compliance decisions.

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