R422D Refrigerant Gas


R422D is an A1 retrofit refrigerant blend used mainly for selected R22 medium- and low-temperature commercial and industrial refrigeration systems.
Its nominal blend is 65.1% R125, 31.5% R134a and 3.4% R600a by mass. Correct retrofit practice still requires system-specific review of capacity, piping, oil return and controls.
Reference packaging includes an 11.3 kg cylinder. Confirm current filling weight, valve configuration and export requirements before ordering.
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Description
R422D Refrigerant Gas
R422D is a zeotropic retrofit refrigerant blend containing nominally 65.1% R125, 31.5% R134a and 3.4% R600a by mass. The finished blend has an A1 safety classification and zero ozone depletion potential.
It was developed primarily for R22 refrigeration retrofits and is used in selected medium- and low-temperature commercial and industrial direct-expansion refrigeration systems. Published retrofit guidance notes that capacity can be lower than R22 depending on the system.
EPA SNAP tables list R422D at a 100-year GWP of 2,730. The blend’s small hydrocarbon component can assist oil circulation in some mineral-oil or alkylbenzene systems, but complex piping or oil hold-up can still require additional lubricant-management steps.
For selection context, review the R22 Refrigerant Replacement Guide and our Commercial Refrigeration application page.
Key R422D Refrigerant Properties
Key composition, safety and transition data for R422D.
R422D Technical Specifications
Established R422D data show a multi-component retrofit blend with A1 classification and zero ODP.
| Refrigerant Designation | R422D |
|---|---|
| Nominal Composition | R125 / R134a / R600a = 65.1 / 31.5 / 3.4 mass % |
| Refrigerant Type | Zeotropic HFC/HC retrofit blend |
| Average Molecular Weight | Approx. 109.9 g/mol |
| Normal Boiling Point | Approx. -43.2°C |
| Critical Temperature | Approx. 79.6°C |
| Critical Pressure | Approx. 39.0 bar |
| Ozone Depletion Potential (ODP) | 0 |
| 100-Year Global Warming Potential | 2,730 — EPA SNAP reference |
| ASHRAE Safety Class | A1 |
| Transport Hazard Class | Class 2.2 |
Physical-property values are reference values; use the current supplier P-T chart, SDS and equipment documentation for actual charging and service work.
Typical R422D Applications
R422D is most relevant to installed R22 refrigeration systems rather than universal new-equipment use.
Medium-Temperature Refrigeration
Selected commercial refrigeration systems operating at medium temperatures can be evaluated for an R422D retrofit.
Low-Temperature Refrigeration
R422D is also used in selected low-temperature direct-expansion refrigeration where the compressor and components are approved.
Cold Storage & Service
Legacy cold rooms, freezer equipment and related R22 refrigeration assets can create R422D service and retrofit demand.
Use our Cold Storage Refrigerants guide and R22 Replacement Guide for broader decision context.
R422D Safety and Handling Considerations
Although R422D is A1, retrofit work must account for blend behavior, pressure, cold-contact hazards and refrigerant recovery.
Blend Handling
Use R422D-specific pressure-temperature data and follow the supplier procedure for charging a zeotropic blend.
Oil Return
The R600a fraction can help oil circulation in some systems, but long piping runs or large oil hold-up volumes can still require engineering review.
Pressure & Recovery
Use rated service equipment, recover refrigerant during service and provide ventilation for significant releases.
R422D is designed for R22 retrofit work, but published guidance notes that refrigeration capacity can be lower and long piping pressure drop can further affect performance. Commission the converted system rather than assuming R22 operating behavior.
R422D Product Specification & Documentation
Product documentation should confirm the blend identity and actual order specification.
| Refrigerant Identity | R422D |
|---|---|
| Nominal Composition | 65.1% R125 / 31.5% R134a / 3.4% R600a |
| Supplied Form | Liquefied compressed refrigerant blend |
| Reference Package | 11.3 kg cylinder |
R422D Refrigerant Packaging Options
The supplied source material supports an 11.3 kg R422D cylinder reference.
| Packaging Type | Reference Size | Supply Note |
|---|---|---|
| Cylinder | 11.3 kg | Service, retrofit and distributor supply |
Confirm current cylinder construction, valve, filling weight, carton configuration and destination-specific transport requirements before ordering.
R422D Is a Practical R22 Refrigeration Retrofit Route
R422D is mainly considered when owners need to keep an existing R22 refrigeration asset in service and an engineered retrofit is preferable to immediate replacement.
The economic decision should include expected capacity, run time, system condition, oil return, leak history, energy use and remaining equipment life.
- Best-known role: medium- and low-temperature R22 direct-expansion refrigeration retrofit.
- Performance review: capacity and pressure-drop effects must be checked after conversion.
- Climate context: GWP 2,730 makes R422D a transition solution rather than a long-term low-GWP platform.
An R22 retrofit can require adjustments to oil management, expansion devices, charge and controls. Follow the compressor, equipment and refrigerant-supplier procedure.
R422D Refrigerant Frequently Asked Questions
What is R422D refrigerant?
R422D is a zeotropic A1 refrigerant blend developed mainly for selected R22 medium- and low-temperature refrigeration retrofits.
What is R422D made of?
Its nominal mass composition is 65.1% R125, 31.5% R134a and 3.4% R600a.
What is the GWP of R422D?
EPA SNAP tables list R422D at a 100-year GWP of 2,730.
Is R422D flammable?
The finished refrigerant is classified A1.
Does R422D have lower capacity than R22?
Published retrofit guidance notes that capacity can be lower in some refrigeration applications, with system design and piping affecting the result.
What package size is available?
The supplied product information includes an 11.3 kg cylinder reference; confirm current order packaging before purchase.
Product information on Refrigerants.net is provided for product identification, comparison and B2B purchasing research. Final refrigerant specification, packaging, availability, transport requirements, permitted use and equipment compatibility should be confirmed against current product documentation, SDS, OEM requirements and applicable regulations before purchase or use.
Additional information
| Application | Cold Storage, Commercial Refrigeration, Retrofit & Service |
|---|---|
| Composition Type | Refrigerant Blend |
| ASHRAE Safety Class | A1 |
| Package Size | 11.3 kg |
| Packaging Type | Disposable Cylinder |
| Refrigerant Number | R422D |
| Transport Hazard Class | Class 2.2 |
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